Concepedia

Studies of the metabolic stability in cells of 5-(trifluoroacetyl)thiophene-2-carboxamides and identification of more stable class II histone deacetylase (HDAC) inhibitors

Rita Scarpelli, Annalise Di Marco, Federica Ferrigno, Ralph Laufer, Isabella Marcucci, Ester Muraglia, Jesus M. Ontoria, Michael Rowley, Sergio Serafini, Christian Steinkühler,

Bioorganic & Medicinal Chemistry Letters · 2008 · 24 citations · 17 references

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17

HDAC6 is a microtubule-associated deacetylase

Charlotte Hubbert, Amaris R. Guardiola, Rong Shao et al. · Nature · 2002 · 2.4K citations

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Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

Madeleine Duvic, Rakshandra Talpur, Xiao Ni et al. · Blood · 2006 · 1.1K citations · Full text

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Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer

William Kevin Kelly, Owen A. O’Connor, Lee M. Krug et al. · Journal of Clinical Oncology · 2005 · 907 citations · Full text

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Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.

Wm. Kevin Kelly, Victoria M. Richon, Owen A. O’Connor et al. · PubMed · 2003 · 623 citations

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Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

Armin Lahm, Chantal Paolini, Michele Pallaoro et al. · Proceedings of the National Academy of Sciences · 2007 · 581 citations · Full text

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