Chantal Paolini

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

Alessandro Vannini, Cinzia Volpari, Gessica Filocamo et al. · Proceedings of the National Academy of Sciences · 2004 · 620 citations · Full text

Histone Modifications, Histone Deacetylases, Crystal Structure +17

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

Armin Lahm, Chantal Paolini, Michele Pallaoro et al. · Proceedings of the National Academy of Sciences · 2007 · 569 citations · Full text

Histone Modifications, Hdac Inhibitors, Epigenetic Change +18

Discovery of Salermide-Related Sirtuin Inhibitors: Binding Mode Studies and Antiproliferative Effects in Cancer Cells Including Cancer Stem Cells

Dante Rotili, Domenico Tarantino, Angela Nebbioso et al. · Journal of Medicinal Chemistry · 2012 · 97 citations · Full text

Oncology, Chemoprevention Strategy, Phenylpropylthio Analogue 4B +14

Molecular Insights into Azumamide E Histone Deacetylases Inhibitory Activity

Nakia Maulucci, Maria Giovanna Chini, Simone Di Micco et al. · Journal of the American Chemical Society · 2007 · 81 citations

Histone Modifications, Drug Target, Bioorganic Chemistry +19

Proteolytic Activation Cascade of the Netherton Syndrome–Defective Protein, LEKTI, in the Epidermis: Implications for Skin Homeostasis

Paola Fortugno, Alberto Bresciani, Chantal Paolini et al. · Journal of Investigative Dermatology · 2011 · 74 citations · Full text

Skin Development, Developmental Biology, Signal Transduction +9