Rita Scarpelli

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 624 citations · Full text

Antiviral Drug, Medicinal Chemistry, Antiviral Drug Development +16

Discovery of 2-{4-[(3<i>S</i>)-Piperidin-3-yl]phenyl}-2<i>H</i>-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors

Philip Jones, Sergio Altamura, Julia K. Boueres et al. · Journal of Medicinal Chemistry · 2009 · 305 citations · Full text

Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

Matthew J. Bottomley, Paola Lo Surdo, Paolo Di Giovine et al. · Journal of Biological Chemistry · 2008 · 302 citations · Full text

Histone Modifications, Histone Deacetylases, Class Iia +17

Chemical synthesis and biological properties of pyridine epothilones

K. C. Nicolaou, Rita Scarpelli, Birgit Bollbuck et al. · Chemistry & Biology · 2000 · 144 citations · Full text

Multitarget Drug Discovery for Alzheimer's Disease: Triazinones as BACE‐1 and GSK‐3β Inhibitors

Federica Prati, Angela De Simone, Paola Bisignano et al. · Angewandte Chemie International Edition · 2014 · 122 citations · Full text

Good Brain Permeability, Neurochemical Biomarkers, Pharmaceutical Chemistry +23