Ester Muraglia

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 634 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Molecular Insights into Quorum Sensing in the Human Pathogen Pseudomonas aeruginosa from the Structure of the Virulence Regulator LasR Bound to Its Autoinducer

Matthew J. Bottomley, Ester Muraglia, Renzo Bazzo · Journal of Biological Chemistry · 2007 · 450 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

Caterina Trozzi, Linda Bartholomew, Alessandra Ceccacci et al. · Journal of Virology · 2003 · 118 citations · Full text

Life Sciences, Biochemistry, Infectious Diseases +17

4,5-Dihydroxypyrimidine Carboxamides and <i>N</i>-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species

Vincenzo Summa, Alessia Petrocchi, Victor G. Matassa et al. · Journal of Medicinal Chemistry · 2006 · 100 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant

Ester Muraglia, Olaf Kinzel, Ralph Laufer et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 90 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14