Matthew J. Bottomley

Molecular Insights into Quorum Sensing in the Human Pathogen Pseudomonas aeruginosa from the Structure of the Virulence Regulator LasR Bound to Its Autoinducer

Matthew J. Bottomley, Ester Muraglia, Renzo Bazzo · Journal of Biological Chemistry · 2007 · 437 citations · Full text

Crystal Structure, Symmetrical Dimer, Quorum Sensing +14

The autoimmune regulator PHD finger binds to non‐methylated histone H3K4 to activate gene expression

Tõnis Org, Francesca Chignola, Csaba Hetényi et al. · EMBO Reports · 2008 · 234 citations · Full text

Molecular Regulation, Epigenetic Change, Immunology +17

Covalent Inhibition of Bacterial Quorum Sensing

Neri Amara, Roi Mashiach, Dotan Amar et al. · Journal of the American Chemical Society · 2009 · 181 citations

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

Tõnis Org, Francesca Chignola, Csaba Hetényi et al. · EMBO Reports · 2008 · 101 citations

Chromatin, Chromatin Structure, Autoimmune Disease +15

NMR Structure of the First PHD Finger of Autoimmune Regulator Protein (AIRE1)

Matthew J. Bottomley, Günter Stier, Danilo Pennacchini et al. · Journal of Biological Chemistry · 2005 · 90 citations · Full text