The autoimmune regulator PHD finger binds to non‐methylated histone H3K4 to activate gene expression

Tõnis Org, Francesca Chignola, Csaba Hetényi, +8

EMBO Reports

Molecular RegulationEpigenetic ChangeImmunologyEpigeneticsTranscriptional Regulation +15

<i>ALOX5AP</i> Gene and the <i>PDE4D</i> Gene in a Central European Population of Stroke Patients

Elin Lõhmussaar, Andreas Gschwendtner, Jakob C. Mueller, +5

Stroke

Scl Represses Cardiomyogenesis in Prospective Hemogenic Endothelium and Endocardium

Ben Van Handel, Amélie Montel‐Hagen, Rajkumar Sasidharan, +16

Cell

Cardiac MuscleCardiomyopathyDevelopmental BiologyCardiac ReprogrammingCardiovascular Disease +6

The Histone Methyltransferase Activity of MLL1 Is Dispensable for Hematopoiesis and Leukemogenesis

Bibhu Prasad Mishra, Kristin M. Zaffuto, Erika L. Artinger, +5

Cell Reports

Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes

Kai Kisand, Maire Link, Anette S. B. Wolff, +19

Blood

Inflammatory Lung DiseaseGeneticsImmunodeficienciesImmunologyImmune Regulation +21

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

Tõnis Org, Francesca Chignola, Csaba Hetényi, +8

EMBO Reports

ChromatinChromatin StructureAutoimmune DiseaseAutoantibody ProductionMedicine +13

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

Francesca Chignola, Massimiliano Gaetani, Ana Rebane, +7

Nucleic Acids Research

Histone H3First Phd FingerEpigenetic ChangeMolecular BiologyEpigenetics +17

AIRE activated tissue specific genes have histone modifications associated with inactive chromatin

Tõnis Org, Ana Rebane, Kai Kisand, +4

Human Molecular Genetics

Histone ModificationsEpigenetic ChangeGeneticsMolecular GeneticsEpigenetics +20

DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity

Ingrid Liiv, Ana Rebane, Tõnis Org, +8

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Dna-pk ContributesMolecular RegulationImmunologyMolecular BiologyAire Protein +16

Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence

Tõnis Org, Dan Duan, Roberto Ferrari, +10

The EMBO Journal

Transcriptional RegulationDevelopmental BiologyCardiac ReprogrammingCardiovascular PhysiologyMedicine +3