<i>ALOX5AP</i> Gene and the <i>PDE4D</i> Gene in a Central European Population of Stroke Patients

Abstract

The present study suggests that sequence variants in the ALOX5AP gene are significantly associated with stroke, particularly in males. Variants in the PDE4D gene are not a major risk factor for stroke in individuals from central Europe. Population differences in allele and haplotype frequencies as well as LD structure may contribute to the observed differences between populations.