Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

Pornpimol Charoentong, Francesca Finotello, Mihaela Angelova, +5

Cell Reports

Machine LearningGenomic LandscapesImmunologyPathologyImmunotherapy +14

Formation of Chromosomal Domains by Loop Extrusion

Geoffrey Fudenberg, Maxim Imakaev, Carolyn Lu, +3

Cell Reports

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

Ángel García-Díaz, Daniel Sanghoon Shin, Blanca Homet Moreno, +16

Cell Reports

A GAL4-Driver Line Resource for Drosophila Neurobiology

Arnim Jenett, Gerald M. Rubin, Teri-T B Ngo, +32

Cell Reports

Drosophila MelanogasterDrosophila NeurobiologyCell LineageDevelopmental BiologyMolecular Neuroscience +11

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

Leticia Corrales, Laura Hix Glickman, Sarah M. McWhirter, +10

Cell Reports

Deciphering Signatures of Mutational Processes Operative in Human Cancer

Ludmil B. Alexandrov, Serena Nik‐Zainal, David C. Wedge, +2

Cell Reports

m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

Qi Cui, Hailing Shi, Peng Ye, +10

Cell Reports

CEL-Seq: Single-Cell RNA-Seq by Multiplexed Linear Amplification

Tamar Hashimshony, Florian Wagner, Noa Sher, +1

Cell Reports

EngineeringGeneticsTranscriptomics TechnologySingle Cell SequencingTranscriptomics +16

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

Schraga Schwartz, Maxwell R. Mumbach, Marko Jovanović, +16

Cell Reports

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyMrna Methylation +20

Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

Andranik Ivanov, Sebastian Memczak, Emanuel Wyler, +8

Cell Reports

BiologyCircrna BiogenesisRna ProcessingSystems BiologyEngineering +13