Olaf Kinzel

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 634 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Synthetic Farnesoid X Receptor Agonists Induce High-Density Lipoprotein-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in Cholesteryl Ester Transfer Protein Transgenic Low-Density Lipoprotein Receptor (−/−) Mice

Eva Hambruch, Shinobu Miyazaki‐Anzai, Ulrike K. Hahn et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 99 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant

Ester Muraglia, Olaf Kinzel, Ralph Laufer et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 90 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

FXR Controls the Tumor Suppressor NDRG2 and FXR Agonists Reduce Liver Tumor Growth and Metastasis in an Orthotopic Mouse Xenograft Model

Ulrich Deuschle, Julia Schüler, Andreas Schulz et al. · PLoS ONE · 2012 · 83 citations · Full text

Medicine, Molecular Biology, Oncology +16

The Synthesis and Antibacterial Activity of two Pyoverdin-ampicillin Conjugates, Entering Pseudomonas aeruginosa via the Pyoverdin-mediated Iron Uptake Pathway.

Olaf Kinzel, Robert Tappe, Igor I. Gerus et al. · The Journal of Antibiotics · 1998 · 66 citations · Full text

Life Sciences, Microbiology, Pharmaceutics +5