HDAC6 is a microtubule-associated deacetylase

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture.

G Piperno, Michel Ledizet, Xiaotian Chang · The Journal of Cell Biology · 1987 · 854 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Deacetylation of p53 modulates its effect on cell growth and apoptosis

Jianyuan Luo, Fei Su, Delin Chen et al. · Nature · 2000 · 824 citations

Life Sciences, Cell Biology, Oncology +12

Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms.

G Piperno, Margaret T. Fuller · The Journal of Cell Biology · 1985 · 765 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Three proteins define a class of human histone deacetylases related to yeast Hda1p

Christina M. Grozinger, Christian A. Hassig, Stuart L. Schreiber · Proceedings of the National Academy of Sciences · 1999 · 762 citations

Life Sciences, Biochemistry, Molecular Biology +13

p300/CBP‐mediated p53 acetylation is commonly induced by p53‐activating agents and inhibited by MDM2

Akihiro Ito, Chun-Hsiang Lai, Xuan Zhao et al. · The EMBO Journal · 2001 · 575 citations · Full text

Medicine, Cancer Biology, Oncology +4