Deacetylation of p53 modulates its effect on cell growth and apoptosis
Nature · 2000 · 820 citations · 25 references
Oncogenic AgentMedicineApoptosisCell DeathCell BiologyTumor SuppressorCell GrowthOncologyRadiation OncologyTumor MicroenvironmentCancer ResearchCancer Growth
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Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
Wei Gu, R G Roeder · Cell · 1997
2.5K citations
A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p
Jack Taunton, Christian A. Hassig, Stuart L. Schreiber · Science · 1996
Histone ModificationsMolecular RegulationEpigenetic Change+19
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DNA damage activates p53 through a phosphorylation–acetylation cascade
Kazuyasu Sakaguchi, Julio E. Herrera, Shinichi Saito et al. · Genes & Development · 1998
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Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
Yi Zhang, Huck‐Hui Ng, H. Erdjument-Bromage et al. · Genes & Development · 1999
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NURD, a Novel Complex with Both ATP-Dependent Chromatin-Remodeling and Histone Deacetylase Activities
Yutong Xue, Jiemin Wong, G. Tony Moreno et al. · Molecular Cell · 1998
Histone ModificationsChromatinHistone Deacetylase Activities+12
976 citations