Shinichi Saito

DNA damage activates p53 through a phosphorylation–acetylation cascade

Kazuyasu Sakaguchi, Julio E. Herrera, Shinichi Saito et al. · Genes & Development · 1998 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

Hwei-Ling Cheng, Raúl Mostoslavsky, Shinichi Saito et al. · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

Tongxiang Lin, Connie Chao, Shinichi Saito et al. · Nature Cell Biology · 2004 · 854 citations

Life Sciences, Genetics, Molecular Biology +13

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Mark Pearson, Roberta Carbone, Carla Sebastiani et al. · Nature · 2000 · 832 citations

Medicine, Cancer Biology, Molecular Biology +16

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

Gabriella D’Orazi, Barbara Cecchinelli, Tiziana Bruno et al. · Nature Cell Biology · 2001 · 679 citations

Life Sciences, Cell Biology, Molecular Biology +14