Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios, +3

Nature Cell Biology

Novel MechanismSystems BiologyNatural SciencesExosome-mediated TransferExtracellular Microvesicles +8

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet, +1

Nature Cell Biology

Mtor Regulate AutophagyMitophagyCell AutophagySignal TransductionSignaling Pathway +8

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Johan Skog, Tom Würdinger, Sjoerd van Rijn, +6

Nature Cell Biology

Neuro-oncologyGliomaTumour GrowthDiagnostic BiomarkersMedicine +8

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

Philip A. Gregory, Andrew G. Bert, Emily Paterson, +6

Nature Cell Biology

Mir-205 Regulate EpithelialEpithelial-mesenchymal TransitionDevelopmental BiologyEpithelial-mesenchymal InteractionsMir-200 Family +7

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

Amparo Cano, Mirna Pérez‐Moreno, Isabel Rodrigo, +5

Nature Cell Biology

Transcriptional RegulationDevelopmental BiologySignaling PathwayMedicineCell Interaction +9

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth, +26

Nature Cell Biology

GlomerulonephritisUrologyRenal FunctionMedicineRenal Failure +10

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu, +2

Nature Cell Biology

Signal TransductionSignaling PathwayCell RegulationSystems BiologyMedicine +3

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huilin Huang, Hengyou Weng, Wenju Sun, +27

Nature Cell Biology

EngineeringRna Binding ProteinsMrna StabilityRna BiologyMolecular Biology +8

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Maria M. Mihaylova, Reuben J. Shaw

Nature Cell Biology

Cell AutophagyMitophagyDevelopmental BiologySignal TransductionSignaling Pathway +10

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

Anne Bertolotti, Yuhong Zhang, Linda M. Hendershot, +2

Nature Cell Biology

Unfolded-protein ResponseReductive StressEr Stress TransducersDynamic InteractionSignal Transduction +12