Christian Steinkühler

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

Alessandro Vannini, Cinzia Volpari, Gessica Filocamo et al. · Proceedings of the National Academy of Sciences · 2004 · 620 citations · Full text

Histone Modifications, Histone Deacetylases, Crystal Structure +17

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

Armin Lahm, Chantal Paolini, Michele Pallaoro et al. · Proceedings of the National Academy of Sciences · 2007 · 569 citations · Full text

Histone Modifications, Hdac Inhibitors, Epigenetic Change +18

Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors

Giulia Minetti, Claudia Colussi, Raffaella Adami et al. · Nature Medicine · 2006 · 323 citations · Full text

Muscle Function, Muscle Injury, Skeletal Muscle +10

Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

Gianluca Canettieri, Lucia Di Marcotullio, Azzura Greco et al. · Nature Cell Biology · 2010 · 321 citations

Molecular Regulation, Epigenetics, Transcriptional Regulation +16

Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

Matthew J. Bottomley, Paola Lo Surdo, Paolo Di Giovine et al. · Journal of Biological Chemistry · 2008 · 302 citations · Full text

Histone Modifications, Histone Deacetylases, Class Iia +17