Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick

Nature Medicine

Hematological MalignancyChromatinCell DivisionMixed-phenotype Acute LeukemiaMalignant Blood Disorder +8

Neurogenesis in the adult human hippocampus

Peter S. Eriksson, Ekaterina Perfilieva, Thomas Björk‐Eriksson, +4

Nature Medicine

Adult Human HippocampusSynaptic PlasticityDevelopmental BiologyMolecular NeuroscienceBrain Structure +11

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Peng Jiang, Shengqing Gu, Deng Pan, +12

Nature Medicine

Cancer ImmunosurveillanceT Cell DysfunctionT-regulatory CellImmunologyTumor Immunity +8

The consensus molecular subtypes of colorectal cancer

Justin Guinney, Rodrigo Dienstmann, Xin Wang, +37

Nature Medicine

MedicinePathologyColorectal CancerCancer GenomicsOncology +2

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Tyler J. Curiel, George Coukos, Linhua Zou, +18

Nature Medicine

Cancer ImmunosurveillanceSpecific RecruitmentT-regulatory CellImmune RegulationImmunology +7

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

Haidong Dong, Scott E. Strome, Diva R. Salomão, +10

Nature Medicine

Immune EvasionCancer ImmunosurveillanceT-cell ApoptosisImmunologyImmunoediting +5

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki, +22

Nature Medicine

Insulin ResistanceMetabolic SyndromeObesityMetabolic DisorderBiochemistry +9

Temporal dynamics in viral shedding and transmissibility of COVID-19

Xi He, Eric H. Y. Lau, Peng Wu, +19

Nature Medicine

Viral PersistenceViral DynamicVirologyCovid-19 EpidemiologyVirus Transmission +3

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

Robert Koeth, Zeneng Wang, Bruce S. Levison, +20

Nature Medicine

NutritionNutrient PhysiologyBiochemistryRed MeatMedicine +9

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Toshimasa Yamauchi, Junji Kamon, Yasuhiko Minokoshi, +17

Nature Medicine

ObesityBiochemistryAmp-activated Protein KinaseFatty-acid OxidationPhysiology +7