Concepedia

Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

Gianluca Canettieri, Lucia Di Marcotullio, Azzura Greco, Sonia Coni, Laura Antonucci, Paola Infante, Laura Pietrosanti, Enrico De Smaele, Elisabetta Ferretti, Evelina Miele,

Nature Cell Biology · 2010 · 325 citations · 36 references

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36

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

Wei Gu, R G Roeder · Cell · 1997 · 2.6K citations · Full text

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Altered Neural Cell Fates and Medulloblastoma in Mouse <i>patched</i> Mutants

Lisa V. Goodrich, Ljiljana Milenković, Kay M. Higgins et al. · Science · 1997 · 1.7K citations

, , +17

Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex

Ning Zheng, Brenda A. Schulman, Langzhou Song et al. · Nature · 2002 · 1.5K citations

, , +9

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Jussi Taipale, James Chen, Michael K. Cooper et al. · Nature · 2000 · 1.3K citations

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Small molecule modulation of Smoothened activity

James Chen, Jussi Taipale, Keith E. Young et al. · Proceedings of the National Academy of Sciences · 2002 · 996 citations

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