Keith E. Young

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Chin Chiang, Ying Litingtung, Eric Lee et al. · Nature · 1996 · 3.1K citations

Life Sciences, Developmental Biology, Genetics +14

Cholesterol Modification of Hedgehog Signaling Proteins in Animal Development

Jeffery A. Porter, Keith E. Young, Philip A. Beachy · Science · 1996 · 1.4K citations

Life Sciences, Biochemistry, Developmental Biology +16

Small molecule modulation of Smoothened activity

James Chen, Jussi Taipale, Keith E. Young et al. · Proceedings of the National Academy of Sciences · 2002 · 996 citations

Life Sciences, Medicinal Chemistry, Pharmacology +13

Teratogen-Mediated Inhibition of Target Tissue Response to <i>Shh</i> Signaling

Michael K. Cooper, Jeffery A. Porter, Keith E. Young et al. · Science · 1998 · 848 citations

Life Sciences, Biochemistry, Pharmacology +17

Hedgehog Patterning Activity: Role of a Lipophilic Modification Mediated by the Carboxy-Terminal Autoprocessing Domain

Jeffery A. Porter, Stephen C. Ekker, Woo-Jin Park et al. · Cell · 1996 · 528 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +14