Paola Infante

Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

Gianluca Canettieri, Lucia Di Marcotullio, Azzura Greco et al. · Nature Cell Biology · 2010 · 321 citations

Molecular Regulation, Epigenetics, Transcriptional Regulation +16

Gli1/ <scp>DNA</scp> interaction is a druggable target for Hedgehog‐dependent tumors

Paola Infante, Mattia Mori, Romina Alfonsi et al. · The EMBO Journal · 2014 · 159 citations · Full text

Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal

Lucia Di Marcotullio, Azzura Greco, Daniela Mazzà et al. · Oncogene · 2010 · 115 citations

Signal Transduction, Novel Degradation Signal, Signaling Pathway +9

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress

Daniela Mazzà, Paola Infante, Valeria Colicchia et al. · Cell Death and Differentiation · 2013 · 93 citations · Full text

Signaling Pathway, Cell Regulation, P53-dependent Response +8

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

Enrico De Smaele, Lucia Di Marcotullio, Marta Moretti et al. · Neoplasia · 2011 · 92 citations · Full text

Kctd Containing, Chromatin, Developmental Biology +11