Structure of Staphylococcal α-Hemolysin, a Heptameric Transmembrane Pore

Langzhou Song, Michael R. Hobaugh, C. Shustak, +3

Science

Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex

Ning Zheng, Brenda A. Schulman, Langzhou Song, +11

Nature

Structural BiologyMolecular BiologyProtein X-ray Crystallography

Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin

James W. Huleatt, Valerian Nakaar, Priyanka Desai, +9

Vaccine

VaccinationCross-protectionVaccine DevelopmentMedicineTlr5 Ligand Flagellin +8

Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity

James W. Huleatt, Andrea R. Jacobs, Jie Tang, +6

Vaccine

VaccinationToll-like ReceptorsCross-protectionAutoimmune DiseaseRecombinant Fusion Proteins +10

Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site

Minsun Hong, Peter S. Lee, Ryan M. B. Hoffman, +9

Journal of Virology

Safety and immunogenicity of a recombinant hemagglutinin influenza–flagellin fusion vaccine (VAX125) in healthy young adults

John J. Treanor, David N. Taylor, Lynda Tussey, +8

Vaccine

VaccinologyVaccine SafetyCross-protectionVaccinationVaccine Development +10

Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response

David N. Taylor, John J. Treanor, Eric Sheldon, +9

Vaccine

VaccinationCross-protectionVaccine DevelopmentRecombinant HemagglutininImmunology +8

α‐Hemolysin, γ‐hemolysin, and leukocidin from <i>Staphylococcus aureus</i>: Distant in sequence but similar in structure

Eric Gouaux, Michael R. Hobaugh, Langzhou Song

Protein Science

Protein SecretionMicrobial PathogensBacteriologyImmunologyMolecular Biology +18

Efficacious Recombinant Influenza Vaccines Produced by High Yield Bacterial Expression: A Solution to Global Pandemic and Seasonal Needs

Langzhou Song, Valerian Nakaar, Uma Kavita, +16

PLoS ONE

Tlr LigandsImmunologyImmunodominanceStrain SelectionPotent Tlr5 Ligand +20

Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin

Langzhou Song, Yi Zhang, Nadezhda E. Yun, +19

Vaccine

VaccinationSuperior EfficacyVaccine DevelopmentMedicineGlobular Head +5