A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates

Joyce Chan, Derek E. Piper, Qiong Cao, +37

Proceedings of the National Academy of Sciences

ImmunologyHyperlipidemiaNonhuman PrimatesImmunotherapyInflammation +16

Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin

James W. Huleatt, Valerian Nakaar, Priyanka Desai, +9

Vaccine

VaccinationCross-protectionVaccine DevelopmentMedicineTlr5 Ligand Flagellin +8

Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity

James W. Huleatt, Andrea R. Jacobs, Jie Tang, +6

Vaccine

VaccinationToll-like ReceptorsCross-protectionAutoimmune DiseaseRecombinant Fusion Proteins +10

Long-acting reversible contraception by effervescent microneedle patch

Wei Li, Jie Tang, Richard N. Terry, +7

Science Advances

A West Nile Virus Recombinant Protein Vaccine That Coactivates Innate and Adaptive Immunity

William F. McDonald, James W. Huleatt, Harald G. Foellmer, +10

The Journal of Infectious Diseases

ImmunologyImmunodominanceInnate ImmunityImmunotherapyArbovirus +15

Efficacious Recombinant Influenza Vaccines Produced by High Yield Bacterial Expression: A Solution to Global Pandemic and Seasonal Needs

Langzhou Song, Valerian Nakaar, Uma Kavita, +16

PLoS ONE

Tlr LigandsImmunologyImmunodominanceStrain SelectionPotent Tlr5 Ligand +20

Liver-Targeted siRNA Lipid Nanoparticles Treat Hepatic Cirrhosis by Dual Antifibrotic and Anti-inflammatory Activities

Jinfang Zhang, Hongwei Shen, Jiaojiao Xu, +12

ACS Nano

Liver FibrosisEngineeringImmunologyHmgb1 GeneBiomedical Engineering +21

Low-intensity red-light therapy in slowing myopic progression and the rebound effect after its cessation in Chinese children: a randomized controlled trial

Hongyan Chen, Wei Wang, Ya Liao, +6

Graefe s Archive for Clinical and Experimental Ophthalmology

Chinese ChildrenRebound EffectPediatricsLow-intensity Red-light TherapyRehabilitation +3

Core-shell microneedle patch for six-month controlled-release contraceptive delivery

Wei Li, Jonathan Yuxuan Chen, Richard N. Terry, +4

Journal of Controlled Release

ContraceptionHormonal ContraceptiveContraceptive ImplantsReproductive HealthBiomedical Engineering +2

PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE

Brandon Ason, José W.A. van der Hoorn, Joyce Chan, +13

Journal of Lipid Research