Concepedia

An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction

Stephen P. East, Samantha J. Bamford, Matthias G. A. Dietz, Christian Eickmeier, Adam Flegg, Boris Ferger, Mark J. Gemkow, Ralf Heilker, Bastian Hengerer, Adrian Kotey,

Bioorganic & Medicinal Chemistry Letters · 2010 · 46 citations · 15 references

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15

Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

Michael J. Marino, David L. Williams, Julie A. O’Brien et al. · Proceedings of the National Academy of Sciences · 2003 · 237 citations · Full text

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Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

Colleen M. Niswender, Kari A. Johnson, C. David Weaver et al. · Molecular Pharmacology · 2008 · 186 citations · Full text

, , +16

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB‐1893 and MPEP

Jesper Mosolff Mathiesen, Nannette Svendsen, Hans Bräuner‐Osborne et al. · British Journal of Pharmacology · 2003 · 171 citations · Full text

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A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

Daniella Rylander Ottosson, Hanna Iderberg, Qin Li et al. · Neurobiology of Disease · 2010 · 151 citations · Full text

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Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease

Andrzej Dekundy, M. Pietraszek, Daniela Schaefer et al. · Brain Research Bulletin · 2006 · 133 citations

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