Stephen P. East

Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ

Lloyd G. Czaplewski, Ian Collins, Edward A. Boyd et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 91 citations

Inhibitory Activity, Biochemistry, Medicine +10

DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity

Stephen P. East, Clara Bantry White, Oliver Barker et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 72 citations

Inhibitory Activity, Medicine, Antibacterial Activity +8

An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines by Calculating the Stabilities of Nitrenium Ions

Jörg Bentzien, Eugene R. Hickey, Raymond A. Kemper et al. · Journal of Chemical Information and Modeling · 2010 · 70 citations

Engineering, Nitrenium Hypothesis, Chemical Analysis +16

An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction

Stephen P. East, Samantha J. Bamford, Matthias G. A. Dietz et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 45 citations · Full text

Motor Dysfunction, Mglu4 Receptor, Medicine +7

The Azulene-to-Naphthalene Rearrangement Revisited:  a DFT Study of Intramolecular and Radical-Promoted Mechanisms

Roger W. Alder, Stephen P. East, Jeremy N. Harvey et al. · Journal of the American Chemical Society · 2003 · 42 citations

Activation Energy, Combinatorial Chemistry, Engineering +14