Eugene R. Hickey

Reversal of H3K9me2 by a Small-Molecule Inhibitor for the G9a Histone Methyltransferase

Stefan Kubicek, Roderick J. O’Sullivan, Elias August et al. · Molecular Cell · 2007 · 841 citations

Histone Modifications, Chromatin, Chromatin Remodeling +12

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

Christopher Pargellis, Liang Tong, Laurie Churchill et al. · Nature Structural Biology · 2002 · 832 citations · Full text

Molecular Pharmacology, Drug Target, Molecular Physiology +11

Pyrazole Urea-Based Inhibitors of p38 MAP Kinase:  From Lead Compound to Clinical Candidate

John R. Regan, Steffen Breitfelder, Pier F. Cirillo et al. · Journal of Medicinal Chemistry · 2002 · 349 citations · Full text

Drug Target, P38 Map Kinase, Atp Binding Site +20

Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase

Kevin Qian, Lian Wang, Eugene R. Hickey et al. · Journal of Biological Chemistry · 2004 · 285 citations · Full text

The kinetics of binding to p38 MAP kinase by analogues of BIRB 796

John R. Regan, Christopher A. Pargellis, Pier F. Cirillo et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 111 citations · Full text