Christopher Pargellis

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

Christopher Pargellis, Liang Tong, Laurie Churchill et al. · Nature Structural Biology · 2002 · 832 citations · Full text

Molecular Pharmacology, Drug Target, Molecular Physiology +11

Characterization of the binding site for nevirapine (BI-RG-587), a nonnucleoside inhibitor of human immunodeficiency virus type-1 reverse transcriptase

K.A. Cohen, John Hopkins, Richard H. Ingraham et al. · Journal of Biological Chemistry · 1991 · 116 citations · Full text

Immunology, Molecular Biology, Antiviral Drug +18

Discovery and Characterization of a Substrate Selective p38α Inhibitor

Walter Davidson, Lee Frego, Gregory W. Peet et al. · Biochemistry · 2004 · 110 citations

Antiviral properties of palinavir, a potent inhibitor of the human immunodeficiency virus type 1 protease

Daniel Lamarre, G Croteau, Elizabeth Wardrop et al. · Antimicrobial Agents and Chemotherapy · 1997 · 74 citations · Full text

Potent Inhibitor, Medicine, Immunology +13

Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis.

Christopher Pargellis, John R. Regan · PubMed · 2003 · 65 citations

Immunology, Cell Death, P38 Inhibitors +17