Christopher A. Pargellis

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

Liang Tong, Susan Pav, Della White et al. · Nature Structural Biology · 1997 · 386 citations

Life Sciences, Biochemistry, Medicinal Chemistry +11

Suicide recombination substrates yield covalent lambda integrase-DNA complexes and lead to identification of the active site tyrosine.

Christopher A. Pargellis, Simone E. Nunes-Düby, Lina Moitoso de Vargas et al. · Journal of Biological Chemistry · 1988 · 190 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Autonomous DNA binding domains of λ integrase recognize two different sequence families

Lina Moitoso de Vargas, Christopher A. Pargellis, Noaman Hasan et al. · Cell · 1988 · 148 citations

Life Sciences, Genetics, Molecular Biology +11

The kinetics of binding to p38 MAP kinase by analogues of BIRB 796

John R. Regan, Christopher A. Pargellis, Pier F. Cirillo et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 111 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Molecular basis of MAPK-activated protein kinase 2:p38 assembly

André White, Christopher A. Pargellis, Joey Studts et al. · Proceedings of the National Academy of Sciences · 2007 · 111 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14