Pier F. Cirillo

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

Christopher Pargellis, Liang Tong, Laurie Churchill et al. · Nature Structural Biology · 2002 · 834 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Pyrazole Urea-Based Inhibitors of p38 MAP Kinase:  From Lead Compound to Clinical Candidate

John R. Regan, Steffen Breitfelder, Pier F. Cirillo et al. · Journal of Medicinal Chemistry · 2002 · 350 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The kinetics of binding to p38 MAP kinase by analogues of BIRB 796

John R. Regan, Christopher A. Pargellis, Pier F. Cirillo et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 111 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-<i>tert</i>-Butyl-2-<i>p</i>-tolyl-2<i>H</i>-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796)

John R. Regan, Alison J. Capolino, Pier F. Cirillo et al. · Journal of Medicinal Chemistry · 2003 · 106 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

A Highly Convergent Total Synthetic Route to Glycopeptides Carrying a High‐Mannose Core Pentasaccharide Domain <i>N</i>‐linked to a Natural Peptide Motif

Samuel J. Danishefsky, Shuanghua Hu, Pier F. Cirillo et al. · Chemistry - A European Journal · 1997 · 87 citations

Life Sciences, Biochemistry, Carbohydrate Biochemistry +15