Oliver Barker

Discovery and characterization of highly potent and selective allosteric USP7 inhibitors

Gérald Gavory, C. O'Dowd, Matthew Helm et al. · Nature Chemical Biology · 2017 · 225 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Binding Mode and Structure–Activity Relationships around Direct Inhibitors of the Nrf2–Keap1 Complex

Eric Jnoff, Claudia Albrecht, John J. Barker et al. · ChemMedChem · 2014 · 174 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity

Stephen P. East, Clara Bantry White, Oliver Barker et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 72 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +13

Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors

C. O'Dowd, Matthew Helm, J. S. Shane Rountree et al. · ACS Medicinal Chemistry Letters · 2018 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +17

The multiple roles of computational chemistry in fragment-based drug design

Richard Law, Oliver Barker, John J. Barker et al. · Journal of Computer-Aided Molecular Design · 2009 · 57 citations

Pharmacy, Chemistry, Medicinal Chemistry +16