Julie A. O’Brien

A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models

Gene G. Kinney, Julie A. O’Brien, Wei Lemaire et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 299 citations

Life Sciences, Neuroscience, Pharmacology +17

Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

Michael J. Marino, David L. Williams, Julie A. O’Brien et al. · Proceedings of the National Academy of Sciences · 2003 · 237 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

A Family of Highly Selective Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 5

Julie A. O’Brien, Wei Lemaire, Tsing‐Bau Chen et al. · Molecular Pharmacology · 2003 · 209 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of 6-(Fluoro-¹⁸<i>F</i>)-3-(1<i>H</i>-pyrrolo[2,3-<i>c</i>]pyridin-1-yl)isoquinolin-5-amine ([¹⁸F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)

Abbas Walji, Eric D. Hostetler, Harold G. Selnick et al. · Journal of Medicinal Chemistry · 2016 · 180 citations

Life Sciences, Neurobiology, Neuroscience +17

A Novel Selective Allosteric Modulator Potentiates the Activity of Native Metabotropic Glutamate Receptor Subtype 5 in Rat Forebrain

Julie A. O’Brien, Wei Lemaire, Marion Wittmann et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 172 citations

Medicine, Neuroscience, Pharmacology +17