N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl- <scp>d</scp> -aspartate receptor activity

Cyrille Sur, Pierre Mallorga, Marion Wittmann, +7

Proceedings of the National Academy of Sciences

Selective activation of the M ₁ muscarinic acetylcholine receptor achieved by allosteric potentiation

Lei Ma, Matthew A. Seager, Marion Wittmann, +25

Proceedings of the National Academy of Sciences

Synaptic TransmissionNeurotransmitterSelective ActivationSocial SciencesMolecular Pharmacology +19

A Novel Selective Allosteric Modulator Potentiates the Activity of Native Metabotropic Glutamate Receptor Subtype 5 in Rat Forebrain

Julie A. O’Brien, Wei Lemaire, Marion Wittmann, +11

Journal of Pharmacology and Experimental Therapeutics

The Glycine Transporter Type 1 Inhibitor<i>N</i>-[3-(4′-Fluorophenyl)-3-(4′-Phenylphenoxy)Propyl]Sarcosine Potentiates NMDA Receptor-Mediated Responses<i>In Vivo</i>and Produces an Antipsychotic Profile in Rodent Behavior

Gene G. Kinney, Cyrille Sur, Maryann Burno, +6

Journal of Neuroscience

Group III Metabotropic Glutamate Receptor-Mediated Modulation of the Striatopallidal Synapse

Ornella Valenti, Michael J. Marino, Marion Wittmann, +4

Journal of Neuroscience

Basal GangliaSynaptic TransmissionNeurotransmitterNeurotransmissionGp Firing Pattern +15

Activation of Group II Metabotropic Glutamate Receptors Inhibits Synaptic Excitation of the Substantia Nigra Pars Reticulata

Stefania Risso Bradley, Michael J. Marino, Marion Wittmann, +4

Journal of Neuroscience

Dopaminergic SystemsNigrostriatal Dopaminergic NeuronsNeurophysiologyMedicineSynaptic Transmission +13

Activation of Group I Metabotropic Glutamate Receptors Produces a Direct Excitation and Disinhibition of GABAergic Projection Neurons in the Substantia Nigra Pars Reticulata

Michael J. Marino, Marion Wittmann, Stefania Risso Bradley, +3

Journal of Neuroscience

Metabotropic Glutamate ReceptorsSynaptic TransmissionNeurotransmitterSnr FunctionsNeurotransmission +16

Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro

Chloe K. Nobuhara, Sarah L. DeVos, Caitlin Commins, +18

American Journal Of Pathology

Neurodegenerative DiseasesLaboratory ImmunologyInterneuron PropagationMedicineCell Trafficking +7

Activation of Group III mGluRs Inhibits GABAergic and Glutamatergic Transmission in the Substantia Nigra Pars Reticulata

Marion Wittmann, Michael J. Marino, Stefania Risso Bradley, +1

Journal of Neurophysiology

The muscarinic M1 receptor positive allosteric modulator PQCA improves cognitive measures in rat, cynomolgus macaque, and rhesus macaque

Jason M. Uslaner, Donnie Eddins, Vanita Puri, +9

Psychopharmacology

Cynomolgus MacaqueNeurophysiologyMedicineRhesus MacaqueNeuropharmacology +7