C. David Weaver

Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels

Melissa Miller, Jie Shi, Yingmin Zhu et al. · Journal of Biological Chemistry · 2011 · 210 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

Colleen M. Niswender, Kari A. Johnson, C. David Weaver et al. · Molecular Pharmacology · 2008 · 186 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

Alice L. Rodriguez, Mark D. Grier, Carrie K. Jones et al. · Molecular Pharmacology · 2010 · 179 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

A Thallium-Sensitive, Fluorescence-Based Assay for Detecting and Characterizing Potassium Channel Modulators in Mammalian Cells

C. David Weaver, David Harden, Steven I. Dworetzky et al. · SLAS DISCOVERY · 2004 · 170 citations · Full text

Natural Sciences, Cell Biology, Pharmacology +17

ML297 (VU0456810), the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice

Kristian Kaufmann, Ian M. Romaine, Emily Days et al. · ACS Chemical Neuroscience · 2013 · 154 citations

Life Sciences, Neuroscience, Pharmacology +17