Foods · 2021 · 29 citations · 38 references
AgricultureFood ScienceToxicologyFood ChemistryFood SafetyFood ToxicologyFood ContaminantsFood Safety AnalysisFood Safety AssessmentFood Safety HazardsFood Safety ToxicologyFood ToxicantsAcrylamide ExposureContaminant OccurrenceCooking-generated CarcinogensFood Contaminant ExposureFood Contaminant ToxicityFood-borne CarcinogensFoodborne CarcinogensFoodborne Chemical Hazards
Acrylamide (also known as 2-propenamide) (AA) is a toxicant that develops in food during high-temperature cooking, and its occurrence is common in biscuits and baked snacks. AA is known for its in vivo neurotoxic and carcinogenic effects, and it is considered a potential carcinogen for humans. Infants may be exposed to AA as early as during weaning through baked food such as biscuits. This study set out to ascertain the concentration of AA in food products intended for infants to assess the dietary exposure to this food contaminant. AA levels were determined through GC/MS and bromination, and dietary exposure was evaluated by a probabilistic method based on Monte Carlo simulation. The results showed that the probability of a carcinogenic exposure is 94%, 92%, and 87%, respectively, for 6-, 12-, and 18-months infants, suggesting the need to delay the introduction of baked products in the diet of weaned infants. It should be noted, however, that these conclusions were drawn considering the biscuits as the primary source of exposure.
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Medicine, Oncology, Toxicology +14
Analysis of Acrylamide, a Carcinogen Formed in Heated Foodstuffs
Eden Tareke, Per Rydberg, Patrik Karlsson et al. · Journal of Agricultural and Food Chemistry · 2002 · 2.2K citations
Scientific Opinion on acrylamide in food
EFSA Journal · 2015 · 817 citations · Full text
Acrylamide: A Cooking Carcinogen?
Eden Tareke, Per Rydberg, Patrik Karlsson et al. · Chemical Research in Toxicology · 2000 · 543 citations
Pharmacy, Biochemistry, Toxicology +17