Concepedia

Identification and molecular docking of peptides from <i>Mizuhopecten yessoensis</i> myosin as human bitter taste receptor T2R14 blockers

Wenzhu Zhao, Donghui Li, Yingxue Wang, Ruotong Kan, Huizhuo Ji, Lijun Su, Zhipeng Yu, Jianrong Li

Food & Function · 2021 · 21 citations · 21 references

DOI

Concepts

Abstract

electrostatic interaction, hydrophobic interaction, conventional hydrogen bond, and hydrogen bond. The novel T2R14 blocking peptide QRPR is a potential candidate for suppressing bitterness.

References

21

Towards the Improved Discovery and Design of Functional Peptides: Common Features of Diverse Classes Permit Generalized Prediction of Bioactivity

Catherine Mooney, Niall Haslam, Gianluca Pollastri et al. · PLoS ONE · 2012 · 582 citations · Full text

, , +16

BitterDB: taste ligands and receptors database in 2019

Ayana Dagan‐Wiener, Antonella Di Pizio, Ido Nissim et al. · Nucleic Acids Research · 2018 · 229 citations · Full text

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Bitter Taste Receptor Activation by Flavonoids and Isoflavonoids: Modeled Structural Requirements for Activation of hTAS2R14 and hTAS2R39

Wibke S. U. Roland, Leo van Buren, Harry Gruppen et al. · Journal of Agricultural and Food Chemistry · 2013 · 207 citations

, , +16

Identification of novel umami peptides from myosin via homology modeling and molecular docking

Zhipeng Yu, Lixin Kang, Wenzhu Zhao et al. · Food Chemistry · 2020 · 137 citations

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Blends of Non-caloric Sweeteners Saccharin and Cyclamate Show Reduced Off-Taste due to TAS2R Bitter Receptor Inhibition

Maik Behrens, Kristina N. Blank, Wolfgang Meyerhof · Cell chemical biology · 2017 · 103 citations · Full text

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