Nature Biotechnology · 2020 · 137 citations · 39 references
EngineeringBioengineeringBiotechnologyProtein EngineeringStructural BiologySynthetic BiologyCrispr-based EngineeringCrispr-cas SystemsProtein DesignEnzyme Scaffold EngineeringPam Sequence RecognitionPam Specificity EngineeringPam-dependent Specificity
39
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
WebLogo: A Sequence Logo Generator: Figure 1
Gavin E. Crooks, Gary C. Hon, John‐Marc Chandonia et al. · Genome Research · 2004 · 13K citations · Full text
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi, Matthew H. Larson, Luke A. Gilbert et al. · Cell · 2013 · 5.2K citations · Full text