Concepedia

Enzyme Scaffold Engineering

Enzyme Scaffold Engineering is a synthetic biology methodology that involves the rational design and construction of modular protein or nucleic acid scaffolds to spatially organize metabolic enzymes, thereby enhancing pathway efficiency and flux by proximity-driven substrate channeling.

38

Publications

3K

Citations

202

Authors

100

Institutions

Publications per year

2017–2026

25

Parents

Publications

38

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm

Jinglin Fu, Yuhe R. Yang, Alexander Johnson‐Buck et al. · Nature Nanotechnology · 2014 · 494 citations

, , +17

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

Tae Seok Moon, John E. Dueber, Eric Shiue et al. · Metabolic Engineering · 2010 · 314 citations · Full text

, , +17

Biocatalytic cascades operating on macromolecular scaffolds and in confined environments

Margarita Vázquez‐González, Chen Wang, Itamar Willner · Nature Catalysis · 2020 · 290 citations

, , +16

Design and Evolution of New Catalytic Activity with an Existing Protein Scaffold

Hee‐Sung Park, Sung-Hun Nam, Jin Kak Lee et al. · Science · 2006 · 280 citations

, , +17

Biomimetic Design of Mitochondria‐Targeted Hybrid Nanozymes as Superoxide Scavengers

Yue Zhang, Anila Khalique, Xinchen Du et al. · Advanced Materials · 2021 · 230 citations

, , +17

1–5 of 38

Authors

202

  1. SL
    Stefan Lutz

    Emory University, United States

    2 publications · 84 citations

    2

    h-index

  2. SJ
    Stephen J. Benkovic

    Pennsylvania State University, United States

    2 publications · 311 citations

    2

    h-index

  3. DB
    David Baker

    University of Washington, United States

    1 publications · 26 citations

    1

    h-index

  4. ML
    Minghui Liu

    Arizona State University, United States

    1 publications · 494 citations

    1

    h-index

  5. JX
    Jiarong Xiong

    Tsinghua University, China

    1 publications · 63 citations

    1

    h-index

1–5 of 202

Institutions

100

  1. Ludwig-Maximilians-Universität München

    Munich, Germany

    2 h-index

    5 publications

    205 citations

  2. Beijing University of Chemical Technology

    Beijing, China

    2 h-index

    10 publications

    818 citations

  3. Center for Integrated Protein Science Munich

    Munich, Germany

    2 h-index

    5 publications

    205 citations

  4. Hebrew University of Jerusalem

    Jerusalem, Israel

    2 h-index

    6 publications

    984 citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    10 publications

    1.9K citations

  6. Pennsylvania State University

    State College, United States

    2 h-index

    11 publications

    2.1K citations

  7. University of California, Berkeley

    Berkeley, United States

    2 h-index

    6 publications

    459 citations

  8. University of Minnesota

    Minneapolis, United States

    2 h-index

    6 publications

    142 citations

1–8 of 100

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 129 citations

    3

    h-index

  2. ACS Synthetic Biology

    3 publications · 140 citations

    3

    h-index

  3. FEBS Journal

    2 publications · 35 citations

    2

    h-index

  4. Chemical Communications

    ChemComm · 2 publications · 46 citations

    2

    h-index

  5. Nature Biotechnology

    1 publications · 137 citations

    1

    h-index

1–5