Concepedia

Crispr-cas Systems

CRISPR-Cas Systems is a class of prokaryotic adaptive immune mechanisms that utilize RNA-guided endonucleases to selectively target and cleave foreign nucleic acids, distinguishing it from other genome editing technologies by its reliance on clustered regularly interspaced short palindromic repeats and associated proteins for programmable DNA recognition and modification.

12.8K

Publications

1.3M

Citations

64K

Authors

6.2K

Institutions

Publications per year

2017–2026

10.4K

Variants

Crispr-cas

Parents

Children

Publications

12.8K

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

, , +17

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

, , +16

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

, , +14

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

, , +15

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau et al. · Science · 2007 · 6.3K citations

, , +17

1–5 of 12.8K

Authors

64K

  1. JA
    Jennifer A. Doudna

    University of California, Berkeley, United States

    152 publications · 68K citations

    91

    h-index

  2. FZ
    Feng Zhang

    Broad Institute, United States

    87 publications · 104K citations

    73

    h-index

  3. JK
    Jin‐Soo Kim

    Seoul National University, South Korea

    75 publications · 22.8K citations

    48

    h-index

  4. EV
    Eugene V. Koonin

    National Center for Biotechnology Information, United States

    77 publications · 28.9K citations

    48

    h-index

  5. GM
    George M. Church

    Harvard University, United States

    69 publications · 28.4K citations

    48

    h-index

1–5 of 64K

Institutions

6.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    178 h-index

    1.3K publications

    508.4K citations

  2. Harvard University

    Cambridge, United States

    178 h-index

    2.7K publications

    933.4K citations

  3. Broad Institute

    Cambridge, United States

    147 h-index

    2K publications

    1.1M citations

  4. University of California, Berkeley

    Berkeley, United States

    131 h-index

    1.6K publications

    445.5K citations

  5. Chinese Academy of Sciences

    Beijing, China

    127 h-index

    3.2K publications

    358.2K citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    125 h-index

    1.1K publications

    726.4K citations

  7. Stanford University

    Stanford, United States

    111 h-index

    1.7K publications

    263K citations

  8. University of California, San Francisco

    San Francisco, United States

    101 h-index

    1.5K publications

    449K citations

1–8 of 6.2K

Venues

  1. Nature Communications

    619 publications · 70.1K citations

    144

    h-index

  2. Nature Biotechnology

    181 publications · 88.9K citations

    117

    h-index

  3. Nucleic Acids Research

    513 publications · 57.2K citations

    111

    h-index

  4. Scientific Reports

    538 publications · 44.3K citations

    110

    h-index

  5. Nature

    164 publications · 68.9K citations

    98

    h-index

1–5