Concepedia

Genome Engineering

Genome Engineering is a molecular engineering discipline that employs designed techniques to deliberately modify an organism's DNA sequences for predetermined functional or phenotypic outcomes.

3.5K

Publications

508.1K

Citations

16.1K

Authors

2.5K

Institutions

Publications per year

2017–2026

1.7K

Parents

Children

Publications

3.5K

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

, , +17

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

, , +16

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

, , +14

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

, , +15

A Broad Host Range Mobilization System for In Vivo Genetic Engineering: Transposon Mutagenesis in Gram Negative Bacteria

Reinhard Simon, U. B. Priefer, Alfred Pühler · Bio/Technology · 1983 · 7.3K citations

, , +12

1–5 of 3.5K

Authors

16.1K

  1. GM
    George M. Church

    Harvard University, United States

    48 publications · 25K citations

    39

    h-index

  2. JA
    Jennifer A. Doudna

    University of California, Berkeley, United States

    45 publications · 32.2K citations

    37

    h-index

  3. JK
    J. Keith Joung

    Massachusetts General Hospital, United States

    45 publications · 24.1K citations

    34

    h-index

  4. FZ
    Feng Zhang

    Broad Institute, United States

    30 publications · 55.5K citations

    29

    h-index

  5. JD
    Jef D. Boeke

    Johns Hopkins University, United States

    27 publications · 7.3K citations

    23

    h-index

1–5 of 16.1K

Institutions

2.5K

  1. Harvard University

    Cambridge, United States

    100 h-index

    820 publications

    505.2K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    95 h-index

    419 publications

    213.2K citations

  3. Chinese Academy of Sciences

    Beijing, China

    67 h-index

    740 publications

    109.9K citations

  4. University of California, Berkeley

    Berkeley, United States

    62 h-index

    400 publications

    167.2K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    61 h-index

    363 publications

    328.2K citations

  6. Broad Institute

    Cambridge, United States

    57 h-index

    419 publications

    422.3K citations

  7. University of Chinese Academy of Sciences

    Beijing, China

    48 h-index

    325 publications

    34.9K citations

  8. Massachusetts General Hospital

    Boston, United States

    46 h-index

    328 publications

    186.7K citations

1–8 of 2.5K

Venues

  1. Nucleic Acids Research

    258 publications · 27.7K citations

    83

    h-index

  2. Nature Communications

    164 publications · 20K citations

    76

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 114 publications · 29.3K citations

    72

    h-index

  4. Nature Biotechnology

    86 publications · 56K citations

    71

    h-index

  5. Scientific Reports

    135 publications · 11.5K citations

    56

    h-index

1–5

See also

Genome Engineering

Core Methods

Applications

Evaluation

Limitations

Delivery Systems