Concepedia

Base Editing

Base Editing is a precise genome engineering technique that enables the direct, programmable conversion of one DNA base pair to another without inducing a double-strand break, thereby allowing for efficient and targeted single-nucleotide modifications.

787

Publications

81.8K

Citations

4.5K

Authors

1K

Institutions

Publications per year

2017–2026

721

Parents

Children

Publications

787

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text

, , +9

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees et al. · Nature · 2017 · 4.2K citations · Full text

, , +12

Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing

Zhen Liu, Zongyang Lu, Guang Yang et al. · Nature Communications · 2018 · 2.1K citations · Full text

, , +16

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

Russell T. Walton, Kathleen A. Christie, Madelynn N. Whittaker et al. · Science · 2020 · 1.3K citations · Full text

, , +15

Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

Michelle F. Richter, Kevin T. Zhao, Elliot O. Eton et al. · Nature Biotechnology · 2020 · 1K citations · Full text

, , +9

1–5 of 787

Authors

4.5K

  1. DR
    David R. Liu

    Harvard University, United States

    54 publications · 22.4K citations

    46

    h-index

  2. GA
    Gregory A. Newby

    Howard Hughes Medical Institute, United States

    25 publications · 6.2K citations

    25

    h-index

  3. XH
    Xingxu Huang

    ShanghaiTech University, China

    27 publications · 4.2K citations

    22

    h-index

  4. JK
    Jin‐Soo Kim

    Seoul National University, South Korea

    22 publications · 3K citations

    20

    h-index

  5. LL
    Liangxue Lai

    Guangzhou Institutes of Biomedicine and Health, China

    21 publications · 1K citations

    19

    h-index

1–5 of 4.5K

Institutions

1K

  1. Harvard University

    Cambridge, United States

    55 h-index

    410 publications

    163.6K citations

  2. Chinese Academy of Sciences

    Beijing, China

    52 h-index

    583 publications

    69K citations

  3. Broad Institute

    Cambridge, United States

    49 h-index

    326 publications

    111.3K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    49 h-index

    251 publications

    128.6K citations

  5. University of Chinese Academy of Sciences

    Beijing, China

    41 h-index

    266 publications

    38.6K citations

  6. ShanghaiTech University

    Shanghai, China

    32 h-index

    258 publications

    44.4K citations

  7. Center for Excellence in Brain Science and Intelligence Technology

    Shanghai, China

    25 h-index

    113 publications

    18.1K citations

  8. Chinese Academy of Agricultural Sciences

    Beijing, China

    24 h-index

    146 publications

    11K citations

1–8 of 1K

Venues

  1. Nature Communications

    99 publications · 9.8K citations

    54

    h-index

  2. Nature Biotechnology

    51 publications · 15K citations

    45

    h-index

  3. Nucleic Acids Research

    41 publications · 2.1K citations

    29

    h-index

  4. Plant Biotechnology Journal

    26 publications · 2.3K citations

    24

    h-index

  5. Molecular Therapy

    20 publications · 1.1K citations

    18

    h-index

1–5