Concepedia

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees, Michael S. Packer, Ahmed H. Badran, David I. Bryson, David R. Liu

Nature · 2017 · 4.2K citations · 40 references

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References

40

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text

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ClinVar: public archive of interpretations of clinically relevant variants

Melissa Landrum, Jennifer M. Lee, Mark J. Benson et al. · Nucleic Acids Research · 2015 · 2.9K citations · Full text

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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai, Zongli Zheng, Nathalie T. Nguyen et al. · Nature Biotechnology · 2014 · 2.3K citations · Full text

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Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems

Keiji Nishida, Takayuki Arazoe, Nozomu Yachie et al. · Science · 2016 · 1.4K citations

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Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

Dominik Paquet, Dylan Kwart, Chen Antonia et al. · Nature · 2016 · 1K citations

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