Ahmed H. Badran

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees et al. · Nature · 2017 · 4K citations · Full text

A Deep Learning Approach to Antibiotic Discovery

Jonathan Stokes, Kevin Yang, Kyle Swanson et al. · Cell · 2020 · 2K citations · Full text

Antimicrobial Drug Discovery, Antimicrobial Susceptibility, Antibiotics +8

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity

Alexis C. Komor, Kevin T. Zhao, Michael S. Packer et al. · Science Advances · 2017 · 759 citations · Full text

Clinically relevant mutations in core metabolic genes confer antibiotic resistance

Allison J. Lopatkin, Sarah C. Bening, Abigail L. Manson et al. · Science · 2021 · 335 citations · Full text

Development of potent in vivo mutagenesis plasmids with broad mutational spectra

Ahmed H. Badran, David R. Liu · Nature Communications · 2015 · 207 citations · Full text