Kevin T. Zhao

Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

Michelle F. Richter, Kevin T. Zhao, Elliot O. Eton et al. · Nature Biotechnology · 2020 · 974 citations · Full text

Engineering, Biochemistry, Natural Sciences +9

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions

Y. Bill Kim, Alexis C. Komor, Jonathan M. Levy et al. · Nature Biotechnology · 2017 · 775 citations · Full text

Engineering, Cas9-cytidine Deaminase Fusions, Synthetic Biology +10

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity

Alexis C. Komor, Kevin T. Zhao, Michael S. Packer et al. · Science Advances · 2017 · 759 citations · Full text

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

Gregory A. Newby, Jonathan Yen, Kaitly J. Woodard et al. · Nature · 2021 · 353 citations · Full text

Base Editing, Cell Therapy, Haematopoietic Stem Cells +9

Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors

Tony P. Huang, Kevin T. Zhao, Shannon M. Miller et al. · Nature Biotechnology · 2019 · 316 citations

Engineering, Pam-modified Cas9 Variants, Molecular Biology +6