Jonathan M. Levy

Search-and-replace genome editing without double-strand breaks or donor DNA

Andrew V. Anzalone, Peyton B. Randolph, Jessie R. Davis et al. · Nature · 2019 · 4.4K citations · Full text

Genome Surgery, Medicine, Genetics +5

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

Luke W. Koblan, Jordan L. Doman, Christopher Wilson et al. · Nature Biotechnology · 2018 · 943 citations · Full text

Bioinformatics, Systems Biology, Molecular Biological Method +13

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions

Y. Bill Kim, Alexis C. Komor, Jonathan M. Levy et al. · Nature Biotechnology · 2017 · 775 citations · Full text

Engineering, Cas9-cytidine Deaminase Fusions, Synthetic Biology +10

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing

Andrew V. Anzalone, Xin D. Gao, Christopher J. Podracky et al. · Nature Biotechnology · 2021 · 532 citations · Full text

Sequence Design, Dna Sequencing, Genome Surgery +14

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses

Jonathan M. Levy, Wei-Hsi Yeh, Nachiket Pendse et al. · Nature Biomedical Engineering · 2020 · 476 citations · Full text

Viral Replication, Molecular Virology, Skeletal Muscle +11