Christopher J. Podracky

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing

Andrew V. Anzalone, Xin D. Gao, Christopher J. Podracky et al. · Nature Biotechnology · 2021 · 532 citations · Full text

Sequence Design, Dna Sequencing, Genome Surgery +14

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

Gregory A. Newby, Jonathan Yen, Kaitly J. Woodard et al. · Nature · 2021 · 353 citations · Full text

Base Editing, Cell Therapy, Haematopoietic Stem Cells +9

Laboratory evolution of a sortase enzyme that modifies amyloid-β protein

Christopher J. Podracky, Chihui An, Alexandra DeSousa et al. · Nature Chemical Biology · 2021 · 61 citations · Full text

Biochemistry, Protein Folding, Natural Sciences +3

Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases

Andrew V. Anzalone, Xin D. Gao, Christopher J. Podracky et al. · 2021 · 18 citations · Full text

Twin Prime Editing, Genetics, Molecular Biology +18

Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product

Emily J. Pomeroy, Andrew V. Anzalone, Christopher J. Podracky et al. · Blood · 2023 · 11 citations