Shannon M. Miller

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

Johnny H. Hu, Shannon M. Miller, Maarten H. Geurts et al. · Nature · 2018 · 1.6K citations

Life Sciences, Genetics, Molecular Biology +12

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

Gregory A. Newby, Jonathan Yen, Kaitly J. Woodard et al. · Nature · 2021 · 380 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Continuous evolution of SpCas9 variants compatible with non-G PAMs

Shannon M. Miller, Tina Wang, Peyton B. Randolph et al. · Nature Biotechnology · 2020 · 357 citations · Full text

Life Sciences, Genetics, Molecular Genetics +8

Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors

Tony P. Huang, Kevin T. Zhao, Shannon M. Miller et al. · Nature Biotechnology · 2019 · 324 citations

Life Sciences, Biotechnology, Molecular Genetics +10

A manganese catalyst for highly reactive yet chemoselective intramolecular C(sp3)–H amination

Shauna M. Paradine, Jennifer R. Griffin, Jinpeng Zhao et al. · Nature Chemistry · 2015 · 275 citations · Full text

Natural Sciences, Chemical Engineering, Chemistry +16