Nature · 2018 · 1.6K citations · 36 references
Life SciencesGeneticsMolecular BiologyGenome EditingGenomicsMolecular EvolutionCrispr-cas SystemsGenetic CodeCas Nuclease Site CompatibilityCrispr-cas9 Genome EditingDna Binding SpecificityPam Sequence RecognitionPam Specificity EngineeringPam-dependent Allele TargetingPam-dependent Specificity
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
WebLogo: A Sequence Logo Generator: Figure 1
Gavin E. Crooks, Gary C. Hon, John‐Marc Chandonia et al. · Genome Research · 2004 · 13K citations · Full text
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Bernd Zetsche, Jonathan S. Gootenberg, Omar O. Abudayyeh et al. · Cell · 2015 · 4.9K citations · Full text
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees et al. · Nature · 2017 · 4.2K citations · Full text