Concepedia

Johnny H. Hu

JH

8

Publications

4K

Citations

8

H-Index

2012

Active since

Affiliations

Harvard University(Current)

Howard Hughes Medical Institute

Broad Institute

Massachusetts Eye and Ear Infirmary

Huazhong University of Science and Technology

Johnny H. Hu is an author at Harvard University specializing in medicine, molecular biology, and genome editing.

Top concepts

MedicineGenome EditingMolecular BiologyGene EditingGeneticsNatural SciencesSynthetic BiologyGenome EngineeringGenetic EngineeringIn Vivo Gene Therapy

Publications per year

2012–2023

8

Publications

8

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

Johnny H. Hu, Shannon M. Miller, Maarten H. Geurts et al. · Nature · 2018 · 1.6K citations · Full text

High Dna Specificity, Genetic Analysis, Allelic Variant +11

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

John A. Zuris, David B. Thompson, Yilai Shu et al. · Nature Biotechnology · 2014 · 1.4K citations · Full text

Lipid Preparation, In Vivo Gene Therapy, Biochemistry +10

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents

Xue Gao, Yong Tao, Verónica Lamas et al. · Nature · 2017 · 532 citations · Full text

Genome Editing Agents, Developmental Biology, In Vivo Gene Therapy +13

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

Weixin Tang, Johnny H. Hu, David R. Liu · Nature Communications · 2017 · 217 citations · Full text

Structure and mechanism of the UvrA–UvrB DNA damage sensor

Danaya Pakotiprapha, Martin A. Samuels, Koning Shen et al. · Nature Structural & Molecular Biology · 2012 · 77 citations

Chromatin, Dna, Dna Damage +4

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