Concepedia

Disease-model Correction

Disease-Model Correction is a research contribution in therapeutic genome editing that consists of a method, model, framework, or dataset designed to rectify pathogenic genetic alterations in cellular or organismal models of disease, thereby restoring phenotypic and molecular features toward a healthy state.

13

Publications

445

Citations

95

Authors

60

Institutions

Publications per year

2017–2026

6

Parents

Publications

13

Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation

Xiaosong Huang, Ying Wang, Wei Yan et al. · Stem Cells · 2015 · 188 citations · Full text

, , +17

Comparison of cytosine base editors and development of the BEable-GPS database for targeting pathogenic SNVs

Ying Wang, Runze Gao, Jing Wu et al. · Genome biology · 2019 · 39 citations · Full text

, , +17

Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes

Elisabeth Mangiameli, Anna Cecchele, Francesco Morena et al. · Stem Cell Reports · 2021 · 33 citations · Full text

, , +17

Cognitive processes and change in disease-model treatment.

Jon Morgenstern, Barbara S. McCrady · 1993 · 33 citations

, , +13

How can we recognize “disease modification” effects?

Eric Siemers · The journal of nutrition health & aging · 2009 · 25 citations · Full text

, , +12

1–5 of 13

Authors

95

  1. EM
    Eliezer M. Van Allen

    Dana-Farber Cancer Institute, United States

    1 publications · 12 citations

    1

    h-index

  2. DL
    David Liu

    Harvard University, United States

    1 publications · 12 citations

    1

    h-index

  3. CR
    Clarice R. Weinberg

    National Institute of Environmental Health Sciences, United States

    1 publications · 15 citations

    1

    h-index

  4. CS
    Cory Smith

    Johns Hopkins Medicine, United States

    1 publications · 188 citations

    1

    h-index

  5. PG
    Peter Gouras

    Columbia University, United States

    1 publications · 13 citations

    1

    h-index

1–5 of 95

Institutions

60

  1. Eli Lilly (United States)

    Indianapolis, United States

    2 h-index

    2 publications

    37 citations

  2. Ulsan College

    Ulsan, South Korea

    1 h-index

    6 publications

    114 citations

  3. Technische Universität Dresden

    Dresden, Germany

    1 h-index

    1 publications

    12 citations

  4. Istituti di Ricovero e Cura a Carattere Scientifico

    Rome, Italy

    1 h-index

    3 publications

    99 citations

  5. Columbia University

    New York, United States

    1 h-index

    11 publications

    143 citations

  6. Johns Hopkins Medicine

    Baltimore, United States

    1 h-index

    2 publications

    376 citations

  7. National and Kapodistrian University of Athens

    Athens, Greece

    1 h-index

    1 publications

    12 citations

  8. Humanitas University

    Rozzano, Italy

    1 h-index

    2 publications

    66 citations

1–8 of 60

Venues

  1. Briefings in Bioinformatics

    1 publications · 18 citations

    1

    h-index

  2. Gene Therapy

    1 publications · 13 citations

    1

    h-index

  3. Nature Medicine

    1 publications · 12 citations

    1

    h-index

  4. Molecular Therapy — Nucleic Acids

    1 publications · 19 citations

    1

    h-index

  5. Biological Theory

    1 publications · 14 citations

    1

    h-index

1–5