Lipid Nanoparticles is a nanoscale delivery vector composed of ionizable lipids, helper lipids, cholesterol, and polyethylene glycol-lipid conjugates that self-assemble into spherical structures capable of encapsulating and protecting nucleic acids for targeted cellular delivery in genome editing applications.
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CAR T cells produced in vivo to treat cardiac injury
Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
Akin Akinc, William Querbes, Soma De et al. · Molecular Therapy · 2010 · 1.2K citations · Full text
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