Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

Dynasore, a Cell-Permeable Inhibitor of Dynamin

Eric Macia, Marcelo Ehrlich, Ramiro Massol et al. · Developmental Cell · 2006 · 2K citations · Full text

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Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.8K citations

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Rab Conversion as a Mechanism of Progression from Early to Late Endosomes

Jochen C. Rink, Éric Ghigo, Yannis Kalaidzidis et al. · Cell · 2005 · 1.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**

Muthusamy Jayaraman, Steven M. Ansell, Barbara L. Mui et al. · Angewandte Chemie International Edition · 2012 · 1.2K citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

Akin Akinc, Andreas Zumbuehl, Michael S. Goldberg et al. · Nature Biotechnology · 2008 · 1.2K citations

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