Concepedia

Genome Synthesis

Genome Synthesis is the comprehensive de novo construction of an organism's entire genome, representing a distinct subfield within genome engineering that entails the chemical assembly of genomic sequences from synthetic nucleotide building blocks, differentiated from related techniques by its focus on creating entire genomes rather than modifying existing ones.

172

Publications

18.1K

Citations

929

Authors

232

Institutions

Publications per year

2017–2026

45

Parents

Children

Publications

172

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

Daniel G. Gibson, John I. Glass, Carole Lartigue et al. · Science · 2010 · 2.7K citations · Full text

, , +17

Design and synthesis of a minimal bacterial genome

Clyde A. Hutchison, Ray-Yuan Chuang, Vladimir N. Noskov et al. · Science · 2016 · 1.5K citations

, , +16

Complete Chemical Synthesis, Assembly, and Cloning of a <i>Mycoplasma genitalium</i> Genome

Daniel G. Gibson, Gwynedd A. Benders, Cynthia Andrews‐Pfannkoch et al. · Science · 2008 · 1.2K citations

, , +17

Proto-genes and de novo gene birth

Anne‐Ruxandra Carvunis, Thomas Rolland, Ilan Wapinski et al. · Nature · 2012 · 710 citations · Full text

, , +10

Generating a synthetic genome by whole genome assembly: φX174 bacteriophage from synthetic oligonucleotides

Hamilton O. Smith, Clyde A. Hutchison, Cynthia Pfannkoch et al. · Proceedings of the National Academy of Sciences · 2003 · 612 citations · Full text

, , +17

1–5 of 172

Authors

929

  1. JD
    Jef D. Boeke

    Johns Hopkins University, United States

    15 publications · 2.6K citations

    14

    h-index

  2. JS
    Joel S. Bader

    Johns Hopkins University, United States

    12 publications · 2.4K citations

    12

    h-index

  3. LA
    Leslie A. Mitchell

    University of British Columbia, Canada

    12 publications · 2.4K citations

    12

    h-index

  4. YC
    Yizhi Cai

    University of Edinburgh, United Kingdom

    9 publications · 2.2K citations

    10

    h-index

  5. JD
    Junbiao Dai

    Shenzhen Institutes of Advanced Technology, China

    8 publications · 859 citations

    9

    h-index

1–5 of 929

Institutions

232

  1. Johns Hopkins University

    Baltimore, United States

    11 h-index

    123 publications

    53.4K citations

  2. University of Edinburgh

    Edinburgh, United Kingdom

    11 h-index

    25 publications

    4.6K citations

  3. NYU Langone Health

    New York, United States

    9 h-index

    45 publications

    9.8K citations

  4. BGI Group (China)

    Shenzhen, China

    9 h-index

    59 publications

    3.6K citations

  5. High Throughput Biology (United States)

    Summit, United States

    8 h-index

    47 publications

    18.8K citations

  6. Institute for Systems Biology

    Seattle, United States

    7 h-index

    70 publications

    2.9K citations

  7. J. Craig Venter Institute

    La Jolla, United States

    7 h-index

    85 publications

    118.8K citations

  8. Harvard University

    Cambridge, United States

    7 h-index

    52 publications

    13.3K citations

1–8 of 232

Venues

  1. Science

    16 publications · 8.4K citations

    16

    h-index

  2. Journal of Molecular Biology

    JMB · 16 publications · 1.1K citations

    15

    h-index

  3. Experimental Cell Research

    ECR · 7 publications · 176 citations

    7

    h-index

  4. Molecular and General Genetics MGG

    7 publications · 242 citations

    7

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 1.5K citations

    7

    h-index

1–5