Erik J. Sontheimer

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

Luciano A. Marraffini, Erik J. Sontheimer · Science · 2008 · 1.7K citations · Full text

Crispr Spacer, Off-target Effect, Engineering +14

Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways

Young Sik Lee, Kenji Nakahara, John Pham et al. · Cell · 2004 · 1.3K citations · Full text

Chromatin, Developmental Biology, Drosophila Dicer-1 +11

Efficient genome engineering in human pluripotent stem cells using Cas9 from <i>Neisseria meningitidis</i>

Zhonggang Hou, Yan Zhang, Nicholas E. Propson et al. · Proceedings of the National Academy of Sciences · 2013 · 685 citations · Full text

Engineering, Crispr-cas Machinery, Molecular Biology +20

Self versus non-self discrimination during CRISPR RNA-directed immunity

Luciano A. Marraffini, Erik J. Sontheimer · Nature · 2010 · 637 citations · Full text

Crispr Rna-directed Immunity, Immunology, Gene Editing +4

A Dicer-2-Dependent 80S Complex Cleaves Targeted mRNAs during RNAi in Drosophila

John Pham, Janice L Pellino, Young Sik Lee et al. · Cell · 2004 · 418 citations · Full text

Natural Sciences, Genetics, Rna Biology +7